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1

Antiparasitic Chemotherapy: From Genomes to Mechanisms

Horn, David, Duraisingh, Manoj T.

Journal:

Annual Review of Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 726 KB

english, 2014

2

Plasmodium vivax transcriptional profiling of low input cryopreserved isolates through the intraerythrocytic development cycle

Rangel, Gabriel W., Clark, Martha A., Kanjee, Usheer, Goldberg, Jonathan M., MacInnis, Bronwyn, JosÃ© Menezes, Maria, Ferreira, Marcelo U., Duraisingh, Manoj T., Barry, Alyssa E.

Journal:

PLoS Neglected Tropical Diseases

Année:

2020

Fichier:

PDF, 5.30 MB

2020

3

A flow cytometry-based assay for measuring invasion of red blood cells by Plasmodium falciparum

Amy K. Bei, Tiffany M. DeSimone, Aida S. Badiane, Ambroise D. Ahouidi, Tandakha Dieye, Daouda Ndiaye, Ousmane Sarr, Omar Ndir, Souleymane Mboup, Manoj T. Duraisingh

Journal:

American Journal of Hematology

Année:

2010

Langue:

english

Fichier:

PDF, 478 KB

english, 2010

4

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors

Carolyn K. Dong, Vishal Patel, Jimmy C. Yang, Jeffrey D. Dvorin, Manoj T. Duraisingh, Jon Clardy, Dyann F. Wirth

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 170 KB

english, 2009

5

Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens

Ambroise D. Ahouidi, Amy K. Bei, Daniel E. Neafsey, Ousmane Sarr, Sarah Volkman, Dan Milner, Janet Cox-Singh, Marcelo U. Ferreira, Omar Ndir, Zul Premji, Souleymane Mboup, Manoj T. Duraisingh

Journal:

Infection, Genetics and Evolution

Année:

2010

Langue:

english

Fichier:

PDF, 279 KB

english, 2010

6

Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum

Manoj T. Duraisingh, Cally Roper, David Walliker, David C. Warhurst

Journal:

Molecular Microbiology

Année:

2000

Langue:

english

Fichier:

PDF, 414 KB

english, 2000

7

Reticulocyte-binding protein homologue 1 is required for sialic acid-dependent invasion into human erythrocytes by Plasmodium falciparum

Tony Triglia, Manoj T. Duraisingh, Robert T. Good, Alan F. Cowman

Journal:

Molecular Microbiology

Année:

2005

Langue:

english

Fichier:

PDF, 398 KB

english, 2005

8

Multiple drug resistance genes in malaria – from epistasis to epidemiology

Manoj T. Duraisingh, Philippe Refour

Journal:

Molecular Microbiology

Année:

2005

Langue:

english

Fichier:

PDF, 163 KB

english, 2005

9

Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum

Katerina Artavanis-Tsakonas, Shahram Misaghi, Christy A. Comeaux, Andre Catic, Eric Spooner, Manoj T. Duraisingh, Hidde L. Ploegh

Journal:

Molecular Microbiology

Année:

2006

Langue:

english

Fichier:

PDF, 410 KB

english, 2006

10

Heterochromatin-mediated control of virulence gene expression

Catherine J. Merrick, Manoj T. Duraisingh

Journal:

Molecular Microbiology

Année:

2006

Langue:

english

Fichier:

PDF, 361 KB

english, 2006

11

Unravelling a histone code for malaria virulence

Christy A. Comeaux, Manoj T. Duraisingh

Journal:

Molecular Microbiology

Année:

2007

Langue:

english

Fichier:

PDF, 125 KB

english, 2007

12

Cooperativity between Plasmodium falciparum adhesive proteins for invasion into erythrocytes

Tiffany M. DeSimone, Cameron V. Jennings, Amy K. Bei, Christy Comeaux, Bradley I. Coleman, Philippe Refour, Tony Triglia, Janine Stubbs, Alan F. Cowman, Manoj T. Duraisingh

Journal:

Molecular Microbiology

Année:

2009

Langue:

english

Fichier:

PDF, 487 KB

english, 2009

13

Functional diversification between two related Plasmodium falciparum merozoite invasion ligands is determined by changes in the cytoplasmic domain

Jeffrey D. Dvorin, Amy K. Bei, Bradley I. Coleman, Manoj T. Duraisingh

Journal:

Molecular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 692 KB

english, 2010

14

Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth

Christy A. Comeaux, Bradley I. Coleman, Amy K. Bei, Nicole Whitehurst, Manoj T. Duraisingh

Journal:

Molecular Microbiology

Année:

2011

Langue:

english

Fichier:

PDF, 790 KB

english, 2011

15

Transcriptional control and gene silencing in Plasmodium falciparum

Bradley I. Coleman, Manoj T. Duraisingh

Journal:

Cellular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 269 KB

english, 2008

16

Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations

Maier, Alexander G., Duraisingh, Manoj T., Reeder, John C., Patel, Sheral S., Kazura, James W., Zimmerman, Peter A., Cowman, Alan F.

Journal:

Nature Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 276 KB

english, 2002

17

Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes

Duraisingh, Manoj T., Triglia, Tony, Ralph, Stuart A., Rayner, Julian C., Barnwell, John W., McFadden, Geoffrey I., Cowman, Alan F.

Journal:

The EMBO Journal

Année:

2003

Langue:

english

Fichier:

PDF, 367 KB

english, 2003

18

Plasmodium falciparum:Detection of Polymorphisms in theDihydrofolate ReductaseandDihydropteroate SynthetaseGenes by PCR and Restriction Digestion

Manoj T. Duraisingh, Jill Curtis, David C. Warhurst

Journal:

Experimental Parasitology

Année:

1998

Langue:

english

Fichier:

PDF, 269 KB

english, 1998

19

Geographical distribution of a variant epitope of Pfs4845, a Plasmodium falciparum transmission-blocking vaccine candidate

Christopher J Drakeley, Manoj T Duraisingh, Marinete Póvoa, David J Conway, Geoffrey A.T Targett, David A Baker

Journal:

Molecular and Biochemical Parasitology

Année:

1996

Langue:

english

Fichier:

PDF, 553 KB

english, 1996

20

Genetic analysis of the cytoplasmic domain of the PfRh2b merozoite invasion protein of Plasmodium falciparum

Tiffany M. DeSimone, Amy K. Bei, Cameron V. Jennings, Manoj T. Duraisingh

Journal:

International Journal for Parasitology

Année:

2009

Langue:

english

Fichier:

PDF, 323 KB

english, 2009

21

The effect of Plasmodium falciparum Sir2a histone deacetylase on clonal and longitudinal variation in expression of the var family of virulence genes

Catherine J. Merrick, Ron Dzikowski, Hideo Imamura, Jeffrey Chuang, Kirk Deitsch, Manoj T. Duraisingh

Journal:

International Journal for Parasitology

Année:

2010

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2010

22

Functional analysis of erythrocyte determinants of Plasmodium infection

Amy K. Bei, Manoj T. Duraisingh

Journal:

International Journal for Parasitology

Année:

2012

Langue:

english

Fichier:

PDF, 635 KB

english, 2012

23

Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania

Amy K. Bei, Christopher D. Membi, Julian C. Rayner, Marycelina Mubi, Billy Ngasala, Ali A. Sultan, Zul Premji, Manoj T. Duraisingh

Journal:

Molecular and Biochemical Parasitology

Année:

2007

Langue:

english

Fichier:

PDF, 394 KB

english, 2007

24

Antisense RNA and RNAi in protozoan parasites: Working hard or hardly working?

Kevin T. Militello, Philippe Refour, Christy A. Comeaux, Manoj T. Duraisingh

Journal:

Molecular and Biochemical Parasitology

Année:

2008

Langue:

english

Fichier:

PDF, 396 KB

english, 2008

25

Erratum to “Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania” [Mol. Biochem. Parasitol. 149 (2006) 208–215]

Amy K. Bei, Christopher D. Membi, Julian C. Rayner, Marycelina Mubi, Billy Ngasala, Ali A. Sultan, Zul Premji, Manoj T. Duraisingh

Journal:

Molecular and Biochemical Parasitology

Année:

2007

Langue:

english

Fichier:

PDF, 69 KB

english, 2007

26

Plasmodium research in the postgenomic era

Manoj Duraisingh, Michael T. Ferdig, Christian J. Stoeckert, Sarah K. Volkman, Victoria P. McGovern

Journal:

Trends in Parasitology

Année:

2006

Langue:

english

Fichier:

PDF, 89 KB

english, 2006

27

Resistance to antiparasitic drugs: the role of molecular diagnosis

Nicholas Sangster, Phillip Batterham, H.David Chapman, Manoj Duraisingh, Leo Le Jambre, Martin Shirley, Jacqui Upcroft, Peter Upcroft

Journal:

International Journal for Parasitology

Année:

2002

Langue:

english

Fichier:

PDF, 185 KB

english, 2002

28

Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination

Manoj T. Duraisingh, Tony Triglia, Alan F. Cowman

Journal:

International Journal for Parasitology

Année:

2002

Langue:

english

Fichier:

PDF, 545 KB

english, 2002

29

The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

Manoj T. Duraisingh, Peter Jones, Idrissa Sambou, Lorenz von Seidlein, Margaret Pinder, David C. Warhurst

Journal:

Molecular and Biochemical Parasitology

Année:

2000

Langue:

english

Fichier:

PDF, 257 KB

english, 2000

30

Contribution of the pfmdr1 gene to antimalarial drug-resistance

Manoj T. Duraisingh, Alan F. Cowman

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 141 KB

english, 2005

31

Malaria evolution in South Asia: Knowledge for control and elimination

Krishnamoorthy Narayanasamy, Laura Chery, Analabha Basu, Manoj T. Duraisingh, Ananias Escalante, Joseph Fowble, Jennifer L. Guler, Thurston Herricks, Ashwani Kumar, Partha Majumder, Jennifer Maki, Anj

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2012

32

Heterochromatin Silencing and Locus Repositioning Linked to Regulation of Virulence Genes in Plasmodium falciparum

Manoj T. Duraisingh, Till S. Voss, Allison J. Marty, Michael F. Duffy, Robert T. Good, Jennifer K. Thompson, Lucio H. Freitas-Junior, Artur Scherf, Brendan S. Crabb, Alan F. Cowman

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 617 KB

english, 2005

33

Efficacy of artesunate plus pyrimethamine-sulphadoxine for uncomplicated malaria in Gambian children: a double-blind, randomised, controlled trial

Lorenz von Seidlein, Paul Milligan, Margaret Pinder, Kalifa Bojang, Chukwudi Anyalebechi, Roland Gosling, Rosalind Coleman, Justin Ifeanyichukwu Ude, Abubakar Sadiq, Manoj Duraisingh, David Warhurst,

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 97 KB

english, 2000

34

Nuclear Repositioning Precedes Promoter Accessibility and Is Linked to the Switching Frequency of a Plasmodium falciparum Invasion Gene

Bradley I. Coleman, Ulf Ribacke, Micah Manary, Amy K. Bei, Elizabeth A. Winzeler, Dyann F. Wirth, Manoj T. Duraisingh

Journal:

Cell Host & Microbe

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

35

Sickle Cell MicroRNAs Inhibit the Malaria Parasite

Manoj T. Duraisingh, Harvey F. Lodish

Journal:

Cell Host & Microbe

Année:

2012

Langue:

english

Fichier:

PDF, 186 KB

english, 2012

36

Evolution of apicomplexan secretory organelles

Marc-Jan Gubbels, Manoj T. Duraisingh

Journal:

International Journal for Parasitology

Année:

2012

Langue:

english

Fichier:

PDF, 710 KB

english, 2012

37

A global transcriptional analysis ofPlasmodium falciparummalaria reveals a novel family of telomere-associated lncRNAs

Kate M Broadbent, Daniel Park, Ashley R Wolf, Daria Van Tyne, Jennifer S Sims, Ulf Ribacke, Sarah Volkman, Manoj Duraisingh, Dyann Wirth, Pardis C Sabeti, John L Rinn

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2011

38

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans

Lim, Caeul, Hansen, Elsa, DeSimone, Tiffany M., Moreno, Yovany, Junker, Klara, Bei, Amy, Brugnara, Carlo, Buckee, Caroline O., Duraisingh, Manoj T.

Journal:

Nature Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1013 KB

english, 2013

39

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

Crosnier, Cécile, Bustamante, Leyla Y., Bartholdson, S. Josefin, Bei, Amy K., Theron, Michel, Uchikawa, Makoto, Mboup, Souleymane, Ndir, Omar, Kwiatkowski, Dominic P., Duraisingh, Manoj T., Rayner, Ju

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 872 KB

english, 2011

40

Human red blood cell-adapted P lasmodium knowlesi parasites: a new model system for malaria research

Grüring, Christof, Moon, Robert W., Lim, Caeul, Holder, Anthony A., Blackman, Michael J., Duraisingh, Manoj T.

Journal:

Cellular Microbiology

Année:

2014

Langue:

english

Fichier:

PDF, 307 KB

english, 2014

41

Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers

Kumar, Ashok A., Lim, Caeul, Moreno, Yovany, Mace, Charles R., Syed, Abeer, Van Tyne, Daria, Wirth, Dyann F., Duraisingh, Manoj T., Whitesides, George M.

Journal:

American Journal of Hematology

Année:

2015

Langue:

english

Fichier:

PDF, 554 KB

english, 2015

42

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

Mejia, Pedro, Treviño-Villarreal, J. Humberto, Hine, Christopher, Harputlugil, Eylul, Lang, Samantha, Calay, Ediz, Rogers, Rick, Wirth, Dyann, Duraisingh, Manoj T., Mitchell, James R.

Journal:

Nature Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2015

43

Specific phosphorylation of the Pf Rh2b invasion ligand of Plasmodium falciparum

Engelberg, Klemens, Paul, Aditya S., Prinz, Boris, Kono, Maya, Ching, Wilhelm, Heincke, Dorothee, Dobner, Thomas, Spielmann, Tobias, Duraisingh, Manoj T., Gilberger, Tim‑Wolf

Journal:

Biochemical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2013

44

In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection

Bei, Amy K., Brugnara, Carlo, Duraisingh, Manoj T.

Journal:

The Journal of Infectious Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 2.82 MB

english, 2010

45

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

Tonkin, Christopher J., Carret, Céline K., Duraisingh, Manoj T., Voss, Till S., Ralph, Stuart A., Hommel, Mirja, Duffy, Michael F., Silva, Liliana Mancio da, Scherf, Artur, Ivens, Alasdair, Speed, Ter

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2009

46

From Protease to Decarboxylase

Choi, Jae-Yeon, Duraisingh, Manoj T., Marti, Matthias, Ben Mamoun, Choukri, Voelker, Dennis R.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2015

47

Editorial overview: Host–microbe interactions: parasites: sensing and responding to the changing environment: the life of protozoan parasites

Guillén, Nancy, Duraisingh, Manoj

Journal:

Current Opinion in Microbiology

Année:

2014

Langue:

english

Fichier:

PDF, 192 KB

english, 2014

48

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity

Ahouidi, Ambroise D., Amambua-Ngwa, Alfred, Awandare, Gordon A., Bei, Amy K., Conway, David J., Diakite, Mahamadou, Duraisingh, Manoj T., Rayner, Julian C., Zenonos, Zenon A.

Journal:

Trends in Parasitology

Année:

2015

Langue:

english

Fichier:

PDF, 5.23 MB

english, 2015

49

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients

Joice, Regina, Frantzreb, Charles, Pradham, Alana, Seydel, Karl B, Kamiza, Steve, Wirth, Dyann F, Duraisingh, Manoj T, Molyneux, Malcolm E, Taylor, Terrie E, Marti, Matthias, Milner Jr, Danny A

Journal:

Modern Pathology

Année:

2016

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2016

50

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca 2+ Signaling

Sidik, Saima M., Hortua Triana, Miryam A., Paul, Aditya S., El Bakkouri, Majida, Hackett, Caroline G., Tran, Fanny, Westwood, Nicholas J., Hui, Raymond, Zuercher, William J., Duraisingh, Manoj T., Mor

Journal:

Journal of Biological Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 3.98 MB

english, 2016